See Nature’s website for more details on our approach to quantify the stability of DNA methylation and the implication of accumulated errors in propagating methylation from mother to daughter cells.
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See Nature’s website for more details on our approach to quantify the stability of DNA methylation and the implication of accumulated errors in propagating methylation from mother to daughter cells.
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Following an earlier work on single cell chromosomal maps (together with Peter Fraser’s group, Yaniv was leading it on our side – paper is here), we have now published Effi’s work on single cell RNA-seq (with Ido Amit’s people, paper is here). The crux of the Hi-C paper is the ability to look at several […]
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The paper is published on Cell 2012. You can find supporting material, including corrected contact maps on this page.
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See paper in Nature Genetics. We intend to release R/perl scripts that normalize Hi-C data in the near future.
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cell paper
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Since the release of the first human reference genome it becomes clearer that the analogy of the genome as the “book of life” (see wikipedia of “genome”) was misleading. While its chapters, paragraphs and footnotes are still elusive, the evidences suggest that genomes of multi-cellular eukaryotes encode information in much more complex ways. The book […]
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Our recent work “Widespread compensatory evolution conserves DNA-encoded nucleosome organization in yeast” is discussed on the February 2011 issue of Nature Reviews Genetics: http://www.nature.com/nrg/journal/v12/n2/full/nrg2946.html#Translational-control
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This paper, published in Genome Research, investigates the association between low copy repeats and translocations: http://genome.cshlp.org/content/21/1/33.full
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