See Nature’s website for more details on our approach to quantify the stability of DNA methylation and the implication of accumulated errors in propagating methylation from mother to daughter cells.
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Published: DNA methylation turnover and epigenetic memory Comments Off on Published: DNA methylation turnover and epigenetic memory
Single cell RNA-seq published Comments Off on Single cell RNA-seq published
Following an earlier work on single cell chromosomal maps (together with Peter Fraser’s group, Yaniv was leading it on our side – paper is here), we have now published Effi’s work on single cell RNA-seq (with Ido Amit’s people, paper is here). The crux of the Hi-C paper is the ability to look at several […]
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Hi-C map of Drosophila is published Comments Off on Hi-C map of Drosophila is published
The paper is published on Cell 2012. You can find supporting material, including corrected contact maps on this page.
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Paper on Hi-C contact map normalization published in Nature Genetics Comments Off on Paper on Hi-C contact map normalization published in Nature Genetics
See paper in Nature Genetics. We intend to release R/perl scripts that normalize Hi-C data in the near future.
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Evolutionary origins of CpG islands paper published in Cell Comments Off on Evolutionary origins of CpG islands paper published in Cell
cell paper
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The book of life? Comments Off on The book of life?
Since the release of the first human reference genome it becomes clearer that the analogy of the genome as the “book of life” (see wikipedia of “genome”) was misleading. While its chapters, paragraphs and footnotes are still elusive, the evidences suggest that genomes of multi-cellular eukaryotes encode information in much more complex ways. The book […]
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Compensatory evolution of nucleosome organization Comments Off on Compensatory evolution of nucleosome organization
Our recent work “Widespread compensatory evolution conserves DNA-encoded nucleosome organization in yeast” is discussed on the February 2011 issue of Nature Reviews Genetics: http://www.nature.com/nrg/journal/v12/n2/full/nrg2946.html#Translational-control
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Paper on human translocations Comments Off on Paper on human translocations
This paper, published in Genome Research, investigates the association between low copy repeats and translocations: http://genome.cshlp.org/content/21/1/33.full
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